Young-Onset Colorectal Cancer Linked to Watching TV

A study from JNCI Cancer Spectrum has found that sedentary behaviors, such as watching TV, lead to a significant increased risk of young-onset colorectal cancer in young Americans.
Rates of young-onset colorectal cancer (CRC) diagnosed before age 50 are increasing globally. This is in contrast to the dramatic decrease of CRC, typically diagnosed in those around age 65, as a result of cancer screening initiatives. According to the study, young-onset CRC has potentially different molecular characteristics compared to late onset. It is typically diagnosed at a more advanced stage than conventional CRC and includes more aggressive tumors, different clinicopathological characteristics, and greater years of life lost. 
The researchers evaluated sedentary behaviors, such as time watching TV, in over 89,278 women, ages 25 to 42 years in the Nurses’ Health Study II. Of the 118 cases of young-onset colorectal cancer diagnosed over 2 decades of follow up, more than 1 hour of daily TV viewing time was associated with a 12% increase in risk compared to those who watched less, according to the study. For those watching 2 hours per day, there was a near 70% increase in risk of young-onset CRC, particularly of the rectum. This association of risk was independent of obesity and exercise and was consistently observed among women without a family history of colorectal cancer. 
"This study may help identify those at high risk and who might benefit more from early screening," Yin Cao, MPH, ScD, Assistant Professor of Surgery at Washington University School of Medicine, and the study's co-senior author, said in a press release. "The fact that these results were independent of BMI and physical activity suggests that being sedentary may be an altogether distinct risk factor for young-onset colorectal cancer."
These findings are among the first to link specific sedentary behavioral patterns with the risk of young-onset colorectal cancer.

Stay up to date on the latest news in specialty pharmacy by getting Specialty Pharmacy Times in your mailbox or inbox for free!

Click here to sign up for free for the bi-monthly Specialty Pharmacy Times print journal delivered to your address.

Click here to sign up for our email newsletters delivered every Monday, Wednesday, and Friday, in addition to breaking news alerts.

Click here to follow us on Facebook. 

Click here to follow us on Twitter. 

Click here to join our LinkedIn group. 

Related Articles

It is important to promote the ongoing development of best practices for integrated specialty pharmacies in academic health systems.
A novel potential biomarker test could identify patients who would benefit from more advanced lung cancer screening.
In addition to a natural variation in genetic makeup, approximately 1 in 1000 people inherit a damaged or mutated copy of the BRCA1 gene from a parent.
Company Profile >
Industry Guide >
Market News >
Peer Exchange >
Conferences >
Subscribe >
Specialty Times Resources
About Us
Contact Us
Terms & Conditions
MJH Associates >
Pharmacy Times
American Journal of Managed Care
MD Magazine
Targeted Oncology
Physicians' Education Resource
Pharmacy & Healthcare Communications, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512
P: 609-716-7777
F: 609-716-4747

Copyright Specialty Pharmacy Times 2006-2019
Pharmacy & Healthcare Communications, LLC. All Rights Reserved.