Pharmacy Refill Data Help Better Identify Nonadherence in Chronic Kidney Disease

Using pharmacy refill data, in addition to provider assessment, helps identify medication nonadherence better than the perceptions of health care providers alone, according to a new study published in Pediatric Nephrology.
Nonadherence to medication regimens can be detrimental to patient outcomes and lead to significant health care costs. In the specialty pharmacy setting, medication adherence is key to patients being treated for chronic and complex conditions. 
In the study, the researchers examined medication nonadherence in a population of young patients with chronic kidney disease. Using 5 different measures of nonadherence, they tracked 87 adolescents and young adults aged 11 through 19 years with chronic kidney disease or end-stage renal disease. The measures of nonadherence were provider reports, patient reports and caregiver reports, electronic pill boxes, and pharmacy refill data.
Providers alone typically make assessments of a patient to identify nonadherence, but individual perceptions are not always accurate. However, technological advances offer additional opportunities to track a patient’s compliance to their treatment.
Based on the findings, health care providers and electronic pillboxes both identified 34.5% of patients as nonadherent, but disagreed about which patients were nonadherent. Additionally, patient reports, caregiver reports, and pharmacy refill data all classified between 50% and 60% of patients as nonadherent. The study showed that combining provider reports and pharmacy refill data provided the the most balanced sensitivity (0.90) and negative predictive power (.88).
The study demonstrates the benefits of using a multimethod approach to identify nonadherence in patients with chronic disease, an essential first step to improve compliance, the researchers concluded.
“In general, providers are already doing assessment of patients’ adherence levels, and most clinical practices have the ability to access pharmacy refill data, so this is a very feasible thing to start doing in a clinical setting,” study author Cozumel Pruette, MD, MHS, assistant professor of pediatrics at Johns Hopkins Children’s Center, said in a press release.
The researchers indicated that more research is needed to determine whether this multimethod approach is also the most effective way to measure adherence levels in other patient populations.
Pruette CS, Coburn SS, Eaton CK, et al. Does a multimodel approach improve identification of medication nonadherence in adolescents with chronic kidney disease? Pediatric Nephrology. 2018.
Study: Technology and Doctors Combine to Detect Patients Who Don’t Take Their Pills [news release]. Johns Hopkins Medicine’s website. Accessed January 3, 2019

Stay up to date on the latest news in specialty pharmacy by getting Specialty Pharmacy Times in your mailbox or inbox for free!

Click here to sign up for free for the bi-monthly Specialty Pharmacy Times print journal delivered to your address.

Click here to sign up for our email newsletters delivered every Monday, Wednesday, and Friday, in addition to breaking news alerts.

Click here to follow us on Facebook. 

Click here to follow us on Twitter. 

Click here to join our LinkedIn group. 

Related Articles

Midazolam (Nayzilam) is indicated for seizures that are distinct from a patient's usual seizure pattern, in individuals age 12 years and older with epilepsy.
Matthew Malachowski, PharmD, BCPS, supervisor of specialty pharmacy services at UAB Health System, discusses how to optimize collaboration among the health care team to prepare for changes that occur throughout the course of a patient's care.
The convenience of home infusion for these products is very enticing for patients who require them and positioning home infusion pharmacies as partners with prescribers and patients is critical to help support this influx of new therapies.
Company Profile >
Industry Guide >
Market News >
Peer Exchange >
Conferences >
Subscribe >
Specialty Times Resources
About Us
Contact Us
Terms & Conditions
MJH Associates >
Pharmacy Times
American Journal of Managed Care
MD Magazine
Targeted Oncology
Physicians' Education Resource
Pharmacy & Healthcare Communications, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512
P: 609-716-7777
F: 609-716-4747

Copyright Specialty Pharmacy Times 2006-2018
Pharmacy & Healthcare Communications, LLC. All Rights Reserved.